1.
Hormones are chemical messengers, produced by gland (exocrine and endocrine)
cells. Hormones can alter the metabolism of target cells . |
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2.
For a hormone to alter a cell's function, that cell must have (express) receptors
for the hormone. Hormone receptors are proteins . |
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3.
Every cell has a subset of hormone receptors, and every cell responds to a number
of different hormones
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4.
Hormones alter cell function by altering the activity of a specific sets of cellular
enzymes. Hormones act through a number of different mechanisms. They
can regulate protein activity or gene expression, or both . |
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5.
Hormones play major roles in sexual reproduction, energy metabolism, water and
electrolyte balance, growth and development, and stress response and immune function
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6.
Hormones generally reach their target cells by transport in the blood and thus
affect cells throughout the body
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7.
The storage and utilization of energy substrates – glucose, fatty
acids, and amino acids – are controlled by hormones. Storage of energy
substrates is controlled by insulin; by its actions promoting glucose storage,
insulin is the primary regulator of blood glucose concentration. Utilization
of energy is controlled by glucagons, epinephrine, cortisol and growth
hormone . |
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8.
Reproductive functions – generation of gametes (eggs and sperm) and the
production of the sex hormones (testosterone and estrogen) – is controlled
by hormonal feedback between the hypothalamus (Define?), the anterior pituitary,
and the gonads (ovaries and testes) . |
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9.
Na+ and K+ balance is regulated by the rennin-angiotensin II-aldosterone system
acting on the kidneys
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10. Body fluid osmolarity is regulated by antidiuretic hormone, related from the
posterior pituitary, acting to control water readsorption by the kidneys
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11.
Reproductive behavior is generated by the interaction of the nervous system (CNS,
ANS and hypothalamus) and the endocrine system
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12.
Ca2+ balance is regulated by parathyroid hormone and calcitonin
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13.
Gametes (sperm and eggs are haploid cells produced in the gonads (testes and
ovaries, respectively) under the control of the hypothalamic-pituitary-gonadal
axis
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