From plakoglobin to Wnt signaling


Fortunately or unforunately, this result yanked us out the relatively mellow world of intermediate filaments and plunked us, rather unexpectedly, into wacky world of Wnt signaling. .

coming soon: anchored plakoglobin and the complex nature of TCF regulation in the early embryo.

 
 

Merriam, J., A. Rubenstein & M.W. Klymkowsky. 1997. Cytoplasmically anchored plakoglobin induces a WNT-like phenotype in Xenopus. Devel. Biol185: 67-81.

M.W. Klymkowsky. 1997. Minireviews, minidogmas, and mythinformation. Bioessays19: 537-539.

M.W. Klymkowsky. 1999. Plakophilin, armadillo repeats and nuclear localization. Microscopy Res. & Tech,43:43-54. 

M.W. Klymkowsky*, B.O. Williams*, G.D. Barish, H.E. Varmus & Y.E. Vourgourakis. 1999. Analysis of membrane-anchored plakoglobins reveals multiple mechanisms of action in Wnt signaling. Mol. Biol Cell.10:3151-3169. (*co-first authors).

Williams, B., G. Barish, M.W. Klymkowsky& H. Varmus. 2000. A comparative evaluation of ß-catenin and plakoglobin signaling sensitivity. Oncogene, 19:5720-8


1953-2004 Michael Klymkowsky and associates
last updated: 7 April 2004
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